The University of Colorado jumped from No. 53 to No. 20 in a recent global ranking of the top 100 universities granted U.S. utility patents for an array of inventions and innovations that can have far-reaching and positive impacts on society.
“This is yet another demonstration of the innovative, entrepreneurial spirit of faculty across the CU system,” said CU President Mark Kennedy. “Our faculty improve lives, save lives and make our state and world a better place. I’m pleased and proud that CU faculty are so adept at securing patents that turn their ideas and research into practical applications that advance a variety of fields.”
Here are the highest-impact patents from 2019 and their associated university spinoffs:
- Inscripta — After raising $260M in investment capital, Inscripta brought the breakthrough digital engineering platform Onyx to market. Inscripta was founded on an exclusive license to a portfolio of CU patents, including US 10,266,849 “CRISPR enabled multiplexed genome engineering” invented by CU Boulder chemical and biological engineering associate professor Ryan Gill. The innovation developed in the Gill lab, known as “CREATE,” enables rapid, multiplexed editing at multiple locations across the genome.
- Kahook Dual Blade - US 10,327,947 “Modified Dual-Blade Cutting System,” was created by Malik Kahook, M.D., CU School of Medicine professor in ophthalmology at the CU Anschutz Medical Campus. The Kahook Dual Blade, launched in 2015 by New World Medical, is a novel surgical blade created to produce a more complete removal of trabecular meshwork, which is the eye tissue associated with the development of glaucoma. Glaucoma is a leading cause of irreversible blindness around the globe. Surgery with the Kahook Dual Blade is minimally invasive and can be effectively performed with equal efficacy in modern operating rooms as well as in low-resource areas around the world. It is now one of the most commonly performed glaucoma procedures and backed by extensive evidence-based medicine.
- Stateless — Stateless, a company reinventing network connectivity, is the exclusive licensee of US 10,245,348 “Stateless Network Functions.” This technology enables new levels of automation, greatly simplifies how businesses access remote IT services and uses computing resources more than five times more cost-effectively than traditional approaches. Lead inventors Eric Keller, a CU Boulder associate professor in electrical, computer and energy engineering, and Murad Kablan (PhDCompSci’17) co-founded Stateless after completing CU Boulder’s New Venture Challenge and Catalyze CU accelerator.
- Q32 Bio — US 10,233,235 “Modulating the Alternative Complement Pathway” application pertains to methods and compositions for modulating, e.g., stimulating or inhibiting, activity of the alternative complement pathway. This therapeutic approach is important because it provides targeted regulation of complement directly in diseased tissues while minimizing the risk of serious infections and other complications associated with systemic complement pathway modulation. The patent is licensed to Q32 Bio, a biotechnology company developing treatments for patients with severe autoimmune and inflammatory diseases. Q32 Bio was seeded and incubated by Atlas Venture with foundational science from renowned researchers in immunology Michael Holers, M.D., and Joshua Thurman, M.D., from the CU School of Medicine at the CU Anschutz Medical Campus. The company raised $46 million in Series A funding and expects to enter into a Phase I trial in 2021.
- Longpath Technologies —US 10,240,998 “Determining a Location and Size of a Gas Source with a Spectrometer Gas Monitor” was created by lead inventor and Longpath co-founder Greg Rieker, a CU Boulder associate professor in mechanical engineering. Rieker, in collaboration with colleagues at CU Boulder and NIST, applied Nobel Prize-winning research on optical frequency combs to detect trace gases with extraordinary sensitivity. LongPath is commercializing cost-effective, continuous gas leak detection and preparing for commercial deployments starting in summer 2020. Rieker also placed first in the 2017 Lab Venture Challenge.
“While patents are a critical part of commercialization, our strategy also heavily emphasizes entrepreneurial training, mentorship and startup resources,” said Brynmor Rees, assistant vice chancellor for Research & Innovation at CU Boulder and managing director of Venture Partners at CU Boulder. “This jump in our ranking shows that our engine of new innovations powers our holistic approach of bringing ideas to market.”
“The University of Colorado’s focus on innovation is yielding impressive results, and we continue to see forward momentum,” said Donald M. Elliman Jr., chancellor of the University of Colorado Anschutz Medical Campus. “At CU Anschutz, our CU Innovations team embodies our collaborative spirit by connecting industry partners with our physicians and researchers in partnerships that lead to diverse projects spanning biomedical technology, novel therapeutics and medical devices. That creative collaboration had led to an increase in patent applications, and growing recognition of our campus as a dynamic hub for commercial innovations that are transforming health care and saving lives.”
The report uses data obtained from the U.S. Patent and Trademark Office (USPTO) and highlights the vital role patents play in university research and innovation.
Published annually since 2013, the report ranks the top 100 universities named as first assignee on utility patents granted by the USPTO in the 2019 calendar year.
“The institutions included in this year’s report are leading innovation worldwide through their encouragement of academic discovery and invention,” said Paul R. Sanberg, NAI president. “We are proud to collaborate with the IPO for the eighth consecutive year to highlight universities that have made critical contributions to society.”
There are 57 member institutions of the NAI represented this year in the Top 100. They hold an aggregate total of 4,685 patents spanning a wide variety of fields, such as medicine, technology and engineering. The IPO Top 300 Patent Owners List, published annually since 1985, ranks organizations worldwide that received the most U.S. utility patents during the previous calendar year.
This year’s report on 2019 patents, published May 18, lists the total number of patents for 2019’s Top 100 universities (including U.S. and international universities) to be 7,873, an increase of 1,046 patents over the previous year.
“University patents ignite a culture of growth and innovation which in turn stimulates the economy,” said Jessica Landacre, IPO executive director. “The Top 100 Worldwide Universities Granted U.S. Utility Patents demonstrates which institutions excel in this arena.”